Distinct Roles of Hand2 in Initiating Polarity and Posterior Shh Expression during the Onset of Mouse Limb Bud Development

The polarization of nascent embryonic fields and the endowment of cells with organizer properties are key to initiation of vertebrate organogenesis. One such event is antero-posterior (AP) polarization of early limb buds and activation of morphogenetic Sonic Hedgehog (SHH) signaling in the posterior...

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Detalhes bibliográficos
Main Authors: Galli, Antonella, Robay, Dimitri, Osterwalder, Marco, Bao, Xiaozhong, Bénazet, Jean-Denis, Tariq, Muhammad, Paro, Renato, Mackem, Susan, Zeller, Rolf
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851570/
https://ncbi.nlm.nih.gov/pubmed/20386744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000901
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