Synthesis and evaluation of substituted hexahydronaphthalenes as novel inhibitors of the Mcl-1/BimBH3 interaction

Eitemau Tebyg

• The BH3 α-Helical Mimic BH3-M6 Disrupts Bcl-X(L), Bcl-2, and MCL-1 Protein-Protein Interactions with Bax, Bak, Bad, or Bim and Induces Apoptosis in a Bax- and Bim-dependent Manner
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  Cyhoeddwyd: (2011)
• Distinct BimBH3 (BimSAHB) Stapled Peptides for Structural and Cellular Studies
  gan: Bird, Greg H., et al.
  Cyhoeddwyd: (2014)
• Marinopyrrole Derivatives with Sulfide Spacers as Selective Disruptors of Mcl-1 Binding to Pro-Apoptotic Protein Bim
  gan: Cheng, Chunwei, et al.
  Cyhoeddwyd: (2014)
• Cyclic Marinopyrrole Derivatives as Disruptors of Mcl-1 and Bcl-x(L) Binding to Bim
  gan: Cheng, Chunwei, et al.
  Cyhoeddwyd: (2014)
• Design, Synthesis and Evaluation of Marinopyrrole Derivatives as Selective Inhibitors of Mcl-1 Binding to Pro-apoptotic Bim and Dual Mcl-1/Bcl-xL Inhibitors
  gan: Li, Rongshi, et al.
  Cyhoeddwyd: (2014)