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The Small Molecule Inhibitor G6 Significantly Reduces Bone Marrow Fibrosis and the Mutant Burden in a Mouse Model of Jak2-Mediated Myelofibrosis

Philadelphia chromosome–negative myeloproliferative neoplasms, including polycythemia vera, essential thrombocytosis, and myelofibrosis, are disorders characterized by abnormal hematopoiesis. Among these myeloproliferative neoplasms, myelofibrosis has the most unfavorable prognosis. Furthermore, cur...

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Detalhes bibliográficos
Main Authors: Kirabo, Annet, Park, Sung O., Wamsley, Heather L., Gali, Meghanath, Baskin, Rebekah, Reinhard, Mary K., Zhao, Zhizhuang J., Bisht, Kirpal S., Keserű, György M., Cogle, Christopher R., Sayeski, Peter P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432437/
https://ncbi.nlm.nih.gov/pubmed/22796437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.05.033
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