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NT-04 THE Jak2 SMALL MOLECULE INHIBITOR, G6, REDUCES THE TUMORIGENIC POTENTIAL OF T98G GLIOBLASTOMA CELLS IN VITRO AND IN VIVO

Glioblastoma multiforme (GBM) is the most common and the most aggressive form of primary brain tumor. Jak2 is a non-receptor tyrosine kinase that is involved in proliferative signaling through its association with various cell surface receptors. Hyperactive Jak2 signaling has been implicated in nume...

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Detalhes bibliográficos
Main Authors: Baskin, Rebekah, Park, Sung, Keseru, Gyorgy, Bisht, Kirpal, Wamsley, Heather, Sayeski, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218449/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou265.4
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