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Biochemical and Mass Spectrometric Characterization of Human N-Acylethanolamine-Hydrolyzing Acid Amidase Inhibition

The mechanism of inactivation of human enzyme N-acylethanolamine-hydrolyzing acid amidase (hNAAA), with selected inhibitors identified in a novel fluorescent based assay developed for characterization of both reversible and irreversible inhibitors, was investigated kinetically and using matrix-assis...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: West, Jay M., Zvonok, Nikolai, Whitten, Kyle M., Vadivel, Subramanian K., Bowman, Anna L., Makriyannis, Alexandros
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432061/
https://ncbi.nlm.nih.gov/pubmed/22952796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043877
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