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Enzymatic synthesis of N-Acylethanolamines: Direct method for the aminolysis of esters

Immobilized Candida antarctica (Novozyme 435) catalyzed synthesis of N-acylethanolamines is described. Treatment of methyl esters with lipase and amines yielded the desired amides within 2–24 hrs with yields ranging from 41–98%.

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Detalhes bibliográficos
Main Authors: Whitten, Kyle M., Makriyannis, Alexandros, Vadivel, Subramanian K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500964/
https://ncbi.nlm.nih.gov/pubmed/23175586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2012.08.042
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