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Enzymatic synthesis of N-Acylethanolamines: Direct method for the aminolysis of esters
Immobilized Candida antarctica (Novozyme 435) catalyzed synthesis of N-acylethanolamines is described. Treatment of methyl esters with lipase and amines yielded the desired amides within 2–24 hrs with yields ranging from 41–98%.
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3500964/ https://ncbi.nlm.nih.gov/pubmed/23175586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2012.08.042 |
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