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Mass Spectrometric Characterization of Human N-acylethanolamine-hydrolyzing Acid Amidase

N-acylethanolamine-hydrolyzing acid amidase (NAAA) is a lysosomal enzyme that primarily degrades palmitoylethanolamine (PEA), a lipid amide that inhibits inflammatory responses. We developed a HEK293 cell line stably expressing the NAAA pro-enzyme (zymogen) and a single step chromatographic purifica...

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Detalhes bibliográficos
Main Authors: West, Jay M., Zvonok, Nikolai, Whitten, Kyle M., Wood, JodiAnne T., Makriyannis, Alexandros
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706083/
https://ncbi.nlm.nih.gov/pubmed/22040171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr200735a
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