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Förster Resonance Energy Transfer (FRET) Correlates of Altered Subunit Stoichiometry in Cys-Loop Receptors, Exemplified by Nicotinic α4β2

We provide a theory for employing Förster resonance energy transfer (FRET) measurements to determine altered heteropentameric ion channel stoichiometries in intracellular compartments of living cells. We simulate FRET within nicotinic receptors (nAChRs) whose α4 and β2 subunits contain acceptor and...

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Autori principali: Srinivasan, Rahul, Richards, Christopher I., Dilworth, Crystal, Moss, Fraser J., Dougherty, Dennis A., Lester, Henry A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Molecular Diversity Preservation International (MDPI) 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431844/
https://ncbi.nlm.nih.gov/pubmed/22949846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms130810022
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