Förster Resonance Energy Transfer (FRET) Correlates of Altered Subunit Stoichiometry in Cys-Loop Receptors, Exemplified by Nicotinic α4β2

We provide a theory for employing Förster resonance energy transfer (FRET) measurements to determine altered heteropentameric ion channel stoichiometries in intracellular compartments of living cells. We simulate FRET within nicotinic receptors (nAChRs) whose α4 and β2 subunits contain acceptor and...

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Main Authors: Srinivasan, Rahul, Richards, Christopher I., Dilworth, Crystal, Moss, Fraser J., Dougherty, Dennis A., Lester, Henry A.
Formato: Artigo
Idioma:Inglês
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Assuntos:
Review
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431844/
https://ncbi.nlm.nih.gov/pubmed/22949846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms130810022
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