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Hypomyelination Phenotype Caused by Impaired Differentiation of Oligodendrocytes in Emx1-cre Mediated Cdk5 Conditional Knockout Mice

Cyclin-dependent kinase 5 (Cdk5) plays a pivotal role in neuronal migration and differentiation, and in axonal elongation. Although many studies have been conducted to analyze neuronal functions of Cdk5, its kinase activity has also been reported during oligodendrocyte differentiation, which suggest...

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Detalhes bibliográficos
Main Authors: He, Xiaojuan, Takahashi, Satoru, Suzuki, Hiromi, Hashikawa, Tsutomu, Kulkarni, Ashok B., Mikoshiba, Katsuhiko, Ohshima, Toshio
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431604/
https://ncbi.nlm.nih.gov/pubmed/21210220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-010-0391-0
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