Understanding transcriptional regulation by integrative analysis of transcription factor binding data

Statistical models have been used to quantify the relationship between gene expression and transcription factor (TF) binding signals. Here we apply the models to the large-scale data generated by the ENCODE project to study transcriptional regulation by TFs. Our results reveal a notable difference i...

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Detalhes bibliográficos
Main Authors: Cheng, Chao, Alexander, Roger, Min, Renqiang, Leng, Jing, Yip, Kevin Y., Rozowsky, Joel, Yan, Koon-Kiu, Dong, Xianjun, Djebali, Sarah, Ruan, Yijun, Davis, Carrie A., Carninci, Piero, Lassman, Timo, Gingeras, Thomas R., Guigó, Roderic, Birney, Ewan, Weng, Zhiping, Snyder, Michael, Gerstein, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431483/
https://ncbi.nlm.nih.gov/pubmed/22955978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.136838.111
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