Understanding transcriptional regulation by integrative analysis of transcription factor binding data

Statistical models have been used to quantify the relationship between gene expression and transcription factor (TF) binding signals. Here we apply the models to the large-scale data generated by the ENCODE project to study transcriptional regulation by TFs. Our results reveal a notable difference i...

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Bibliografiske detaljer
Main Authors: Cheng, Chao, Alexander, Roger, Min, Renqiang, Leng, Jing, Yip, Kevin Y., Rozowsky, Joel, Yan, Koon-Kiu, Dong, Xianjun, Djebali, Sarah, Ruan, Yijun, Davis, Carrie A., Carninci, Piero, Lassman, Timo, Gingeras, Thomas R., Guigó, Roderic, Birney, Ewan, Weng, Zhiping, Snyder, Michael, Gerstein, Mark
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2012
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431483/
https://ncbi.nlm.nih.gov/pubmed/22955978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.136838.111
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