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Role of Endoplasmic Reticulum Aminopeptidases in Health and Disease: from Infection to Cancer
Endoplasmic reticulum (ER) aminopeptidases ERAP1 and ERAP2 (ERAPs) are essential for the maturation of a wide spectrum of proteins involved in various biological processes. In the ER, these enzymes work in concert to trim peptides for presentation on MHC class I molecules. Loss of ERAPs function sub...
Tallennettuna:
| Päätekijät: | , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Molecular Diversity Preservation International (MDPI)
2012
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3430237/ https://ncbi.nlm.nih.gov/pubmed/22942706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms13078338 |
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