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ERAAP modulation: A possible novel strategy for cancer immunotherapy?

Recent findings demonstrate that loss of ERAAP, an endoplasmic reticulum aminopeptidase involved in antigen processing, plays a key role in stimulating anti-tumor innate and adaptive immune responses. We show that MHC class I molecules produced in the absence of ERAAP retain their capability of pres...

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Detalhes bibliográficos
Main Authors: Fruci, Doriana, Locatelli, Franco, Cifaldi, Loredana
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3376965/
https://ncbi.nlm.nih.gov/pubmed/22720218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.1.1.17828
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