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Endoplasmic reticulum aminopeptidase 1 and rheumatic disease: functional variation
PURPOSE OF REVIEW: To review recent developments in our understanding of endoplasmic reticulum (ER) aminopeptidase-1 (ERAP1) function in relation to its role in MHC class I peptide presentation and HLA class I-associated diseases. RECENT FINDINGS: ERAP1 polymorphisms exhibiting loss-of-function have...
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| Publicado no: | Curr Opin Rheumatol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4495904/ https://ncbi.nlm.nih.gov/pubmed/26002027 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/BOR.0000000000000188 |
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