Paternal Benzo[a]pyrene Exposure Affects Gene Expression in the Early Developing Mouse Embryo

The health of the offspring depends on the genetic constitution of the parental germ cells. The paternal genome appears to be important; e.g., de novo mutations in some genes seem to arise mostly from the father, whereas epigenetic modifications of DNA and histones are frequent in the paternal gonad...

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Autors principals: Brevik, Asgeir, Lindeman, Birgitte, Rusnakova, Vendula, Olsen, Ann-Karin, Brunborg, Gunnar, Duale, Nur
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3430208/
https://ncbi.nlm.nih.gov/pubmed/22641617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfs187
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