Paternal Benzo[a]pyrene Exposure Affects Gene Expression in the Early Developing Mouse Embryo

The health of the offspring depends on the genetic constitution of the parental germ cells. The paternal genome appears to be important; e.g., de novo mutations in some genes seem to arise mostly from the father, whereas epigenetic modifications of DNA and histones are frequent in the paternal gonad...

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Autori principali: Brevik, Asgeir, Lindeman, Birgitte, Rusnakova, Vendula, Olsen, Ann-Karin, Brunborg, Gunnar, Duale, Nur
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3430208/
https://ncbi.nlm.nih.gov/pubmed/22641617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfs187
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