Subchronic Oral Exposure to Benzo(a)pyrene Leads to Distinct Transcriptomic Changes in the Lungs That Are Related to Carcinogenesis

We have previously shown that acute oral exposure to the environmental carcinogen benzo(a)pyrene (BaP) elicits comparable levels of DNA adducts, but distinct transcriptomic changes, in mouse lungs and livers, the two main BaP bioactivating organs. Oral BaP exposure is predominantly associated with l...

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Detalles Bibliográficos
Main Authors: Labib, Sarah, Yauk, Carole, Williams, Andrew, Arlt, Volker M., Phillips, David H., White, Paul A., Halappanavar, Sabina
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2012
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3430207/
https://ncbi.nlm.nih.gov/pubmed/22610609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfs177
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