Transcriptional profiling of the mouse hippocampus supports an NMDAR‐mediated neurotoxic mode of action for benzo[a]pyrene

Benzo[a]pyrene (BaP) is a genotoxic carcinogen and a neurotoxicant. The neurotoxicity of BaP is proposed to arise from either genotoxicity leading to neuronal cell death, or perturbed expression of N‐methyl‐d‐aspartate receptor (NMDAR) subunits. To explore these hypotheses, we profiled hippocampal g...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Environ Mol Mutagen
Main Authors: Chepelev, Nikolai L., Long, Alexandra S., Bowers, Wayne J., Gagné, Rémi, Williams, Andrew, Kuo, Byron, Phillips, David H., Arlt, Volker M., White, Paul A., Yauk, Carole L.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915531/
https://ncbi.nlm.nih.gov/pubmed/27195522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.22020
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados