Subchronic Oral Exposure to Benzo(a)pyrene Leads to Distinct Transcriptomic Changes in the Lungs That Are Related to Carcinogenesis

We have previously shown that acute oral exposure to the environmental carcinogen benzo(a)pyrene (BaP) elicits comparable levels of DNA adducts, but distinct transcriptomic changes, in mouse lungs and livers, the two main BaP bioactivating organs. Oral BaP exposure is predominantly associated with l...

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Detalhes bibliográficos
Main Authors: Labib, Sarah, Yauk, Carole, Williams, Andrew, Arlt, Volker M., Phillips, David H., White, Paul A., Halappanavar, Sabina
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3430207/
https://ncbi.nlm.nih.gov/pubmed/22610609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfs177
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