Subchronic Oral Exposure to Benzo(a)pyrene Leads to Distinct Transcriptomic Changes in the Lungs That Are Related to Carcinogenesis

We have previously shown that acute oral exposure to the environmental carcinogen benzo(a)pyrene (BaP) elicits comparable levels of DNA adducts, but distinct transcriptomic changes, in mouse lungs and livers, the two main BaP bioactivating organs. Oral BaP exposure is predominantly associated with l...

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Bibliografski detalji
Glavni autori: Labib, Sarah, Yauk, Carole, Williams, Andrew, Arlt, Volker M., Phillips, David H., White, Paul A., Halappanavar, Sabina
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2012
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3430207/
https://ncbi.nlm.nih.gov/pubmed/22610609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfs177
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