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The Hypersensitive Glucocorticoid Response Specifically Regulates Period 1 and Expression of Circadian Genes

Glucocorticoids regulate gene expression by binding and activating the glucocorticoid receptor (GR). While ligand affinity determines the global sensitivity of the response, additional proteins act on the genome to tune sensitivity of some genes. However, the genomic extent and specificity of dose-s...

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Autors principals: Reddy, Timothy E., Gertz, Jason, Crawford, Gregory E., Garabedian, Michael J., Myers, Richard M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3430195/
https://ncbi.nlm.nih.gov/pubmed/22801371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00062-12
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