Innate immune recognition of breast tumor cells mediates CCL22 secretion favoring Treg recruitment within tumor environment

Regulatory T cells (Treg) have been reported of poor prognosis for overall survival in primary breast tumors (BT). As CCL22 plays a major role in Treg recruitment within primary BT we deciphered the mechanisms involved in the CCL22 production by breast epithelial tumor cells and propose herein the m...

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Hauptverfasser: Ménétrier-Caux, Christine, Faget, Julien, Biota, Cathy, Gobert, Michael, Blay, Jean-Yves, Caux, Christophe
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2012
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429586/
https://ncbi.nlm.nih.gov/pubmed/22934274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.19680
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