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Environment-mediated drug resistance in Bcr/Abl-positive acute lymphoblastic leukemia

Although cure rates for acute lymphoblastic leukemia (ALL) have increased, development of resistance to drugs and patient relapse are common. The environment in which the leukemia cells are present during the drug treatment is known to provide significant survival benefit. Here, we have modeled this...

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Hlavní autoři: Feldhahn, Niklas, Arutyunyan, Anna, Stoddart, Sonia, Zhang, Bin, Schmidhuber, Sabine, Yi, Sun-Ju, Kim, Yong-mi, Groffen, John, Heisterkamp, Nora
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429566/
https://ncbi.nlm.nih.gov/pubmed/22934254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.20249
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