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Nilotinib treatment in mouse models of P190 Bcr/Abl lymphoblastic leukemia
BACKGROUND: Ph-positive leukemias are caused by the aberrant fusion of the BCR and ABL genes. Nilotinib is a selective Bcr/Abl tyrosine kinase inhibitor related to imatinib, which is widely used to treat chronic myelogenous leukemia. Because Ph-positive acute lymphoblastic leukemia only responds tra...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2169263/ https://ncbi.nlm.nih.gov/pubmed/17958915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-6-67 |
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