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Resistance to farnesyltransferase inhibitors in Bcr/Abl-positive lymphoblastic leukemia by increased expression of a novel ABC transporter homolog ATP11a

Resistance to cytotoxic drugs frequently emerges during treatment of leukemia with conventional chemotherapy. New classes of anticancer drugs, such as the farnesyltransferase inhibitors (FTIs), show therapeutic promise, but whether cells will easily develop resistance against them is not known. Here...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhang, Bin, Groffen, John, Heisterkamp, Nora
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society of Hematology 2005
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895195/
https://ncbi.nlm.nih.gov/pubmed/15860663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-09-3655
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