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Cleavage of Nidogen-1 by Cathepsin S Impairs Its Binding to Basement Membrane Partners
Cathepsin S (catS), which is expressed in normal human keratinocytes and localized close to the dermal-epidermal junction (DEJ) degrades some of major basement membrane (BM) constituents. Among them, catS readily hydrolyzed in a time and dose dependent manner human nidogen-1 (nid-1) and nidogen-2, w...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3429489/ https://ncbi.nlm.nih.gov/pubmed/22952693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043494 |
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