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Role of modified nucleosides in tRNA: effect of modification of the 2-thiouridine derivative located at the 5'-end of the anticodon of yeast transfer RNA Lys2.

Yeast tRNA Lys2 codes preferentially for AAA and contains a 2-thiouridine derivative (U) at the 5'-position of the anticodon. Removal of the 2-thio group from U by treatment with CNBr did not affect the amino acid accepting activity of the modified tRNA Lys2. CNBr treated tRNA Lys2 was active i...

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Detalhes bibliográficos
Main Authors: Sen, G C, Ghosh, H P
Formato: Artigo
Idioma:Inglês
Publicado em: 1976
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC342923/
https://ncbi.nlm.nih.gov/pubmed/775440
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