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Period2 gene mutant mice show compromised insulin-mediated endothelial nitric oxide release and altered glucose homeostasis

Period2 (Per2) is an important component of the circadian clock. Mutation of this gene is associated with vascular endothelial dysfunction and altered glucose metabolism. The aim of this study is to further characterize whole body glucose homeostasis and endothelial nitric oxide (NO) production in r...

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Autors principals: Carvas, João M., Vukolic, Ana, Yepuri, Gautham, Xiong, Yuyan, Popp, Katja, Schmutz, Isabelle, Chappuis, Sylvie, Albrecht, Urs, Ming, Xiu-Fen, Montani, Jean-Pierre, Yang, Zhihong
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429102/
https://ncbi.nlm.nih.gov/pubmed/22934083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2012.00337
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