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Period2 gene mutant mice show compromised insulin-mediated endothelial nitric oxide release and altered glucose homeostasis

Period2 (Per2) is an important component of the circadian clock. Mutation of this gene is associated with vascular endothelial dysfunction and altered glucose metabolism. The aim of this study is to further characterize whole body glucose homeostasis and endothelial nitric oxide (NO) production in r...

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Detalhes bibliográficos
Main Authors: Carvas, João M., Vukolic, Ana, Yepuri, Gautham, Xiong, Yuyan, Popp, Katja, Schmutz, Isabelle, Chappuis, Sylvie, Albrecht, Urs, Ming, Xiu-Fen, Montani, Jean-Pierre, Yang, Zhihong
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429102/
https://ncbi.nlm.nih.gov/pubmed/22934083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2012.00337
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