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ARG2 impairs endothelial autophagy through regulation of MTOR and PRKAA/AMPK signaling in advanced atherosclerosis

Impaired autophagy function and enhanced ARG2 (arginase 2)-MTOR (mechanistic target of rapamycin) crosstalk are implicated in vascular aging and atherosclerosis. We are interested in the role of ARG2 and the potential underlying mechanism(s) in modulation of endothelial autophagy. Using human nonsen...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Xiong, Yuyan, Yepuri, Gautham, Forbiteh, Michael, Yu, Yi, Montani, Jean-Pierre, Yang, Zhihong, Ming, Xiu-Fen
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502672/
https://ncbi.nlm.nih.gov/pubmed/25484082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15548627.2014.981789
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