PRKAA1/AMPKα1-driven glycolysis in endothelial cells exposed to disturbed flow protects against atherosclerosis

Increased aerobic glycolysis in endothelial cells of atheroprone areas of blood vessels has been hypothesized to drive increased inflammation and lesion burden but direct links remain to be established. Here we show that endothelial cells exposed to disturbed flow in vivo and in vitro exhibit increa...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Yang, Qiuhua, Xu, Jiean, Ma, Qian, Liu, Zhiping, Sudhahar, Varadarajan, Cao, Yapeng, Wang, Lina, Zeng, Xianqiu, Zhou, Yaqi, Zhang, Min, Xu, Yiming, Wang, Yong, Weintraub, Neal L., Zhang, Chunxiang, Fukai, Tohru, Wu, Chaodong, Huang, Lei, Han, Zhen, Wang, Tao, Fulton, David J., Hong, Mei, Huo, Yuqing
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6220207/
https://ncbi.nlm.nih.gov/pubmed/30405100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07132-x
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