Ablation of myeloid adenosine kinase epigenetically suppresses atherosclerosis in apolipoprotein E-deficient mice

OBJECTIVE: Monocyte-derived foam cells are one of the key players in the formation of atherosclerotic plaques. Adenosine receptors and extracellular adenosine have been demonstrated to modulate foam cell formation. Adenosine kinase (ADK) is a major enzyme regulating intracellular adenosine levels, b...

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Udgivet i:Arterioscler Thromb Vasc Biol
Main Authors: Zhang, Min, Zeng, Xianqiu, Yang, Qiuhua, Xu, Jiean, Liu, Zhiping, Zhou, Yaqi, Cao, Yapeng, Zhang, Xiaoyu, An, Xiaofei, Xu, Yiming, Huang, Lei, Han, Zhen, Wang, Tao, Wu, Chaodong, Fulton, David J, Weintraub, Neal L, Hong, Mei, Huo, Yuqing
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6309817/
https://ncbi.nlm.nih.gov/pubmed/30571174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.118.311806
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