Ablation of myeloid adenosine kinase epigenetically suppresses atherosclerosis in apolipoprotein E-deficient mice

OBJECTIVE: Monocyte-derived foam cells are one of the key players in the formation of atherosclerotic plaques. Adenosine receptors and extracellular adenosine have been demonstrated to modulate foam cell formation. Adenosine kinase (ADK) is a major enzyme regulating intracellular adenosine levels, b...

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發表在:Arterioscler Thromb Vasc Biol
Main Authors: Zhang, Min, Zeng, Xianqiu, Yang, Qiuhua, Xu, Jiean, Liu, Zhiping, Zhou, Yaqi, Cao, Yapeng, Zhang, Xiaoyu, An, Xiaofei, Xu, Yiming, Huang, Lei, Han, Zhen, Wang, Tao, Wu, Chaodong, Fulton, David J, Weintraub, Neal L, Hong, Mei, Huo, Yuqing
格式: Artigo
語言:Inglês
出版: 2018
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6309817/
https://ncbi.nlm.nih.gov/pubmed/30571174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.118.311806
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