Regulation of endothelial intracellular adenosine via adenosine kinase epigenetically modulates vascular inflammation

The molecular mechanisms underlying vascular inflammation and associated inflammatory vascular diseases are not well defined. Here we show that endothelial intracellular adenosine and its key regulator adenosine kinase (ADK) play important roles in vascular inflammation. Pro-inflammatory stimuli lea...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Xu, Yiming, Wang, Yong, Yan, Siyuan, Yang, Qiuhua, Zhou, Yaqi, Zeng, Xianqiu, Liu, Zhiping, An, Xiaofei, Toque, Haroldo A., Dong, Zheng, Jiang, Xuejun, Fulton, David J., Weintraub, Neal L., Li, Qinkai, Bagi, Zsolt, Hong, Mei, Boison, Detlev, Wu, Chaodong, Huo, Yuqing
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5643397/
https://ncbi.nlm.nih.gov/pubmed/29038540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00986-7
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