Pressure overload-induced mild cardiac hypertrophy reduces left ventricular transmural differences in mitochondrial respiratory chain activity and increases oxidative stress

Objective: Increased mechanical stress and contractility characterizes normal left ventricular (LV) subendocardium (Endo) but whether Endo mitochondrial respiratory chain complex activities is reduced as compared to subepicardium (Epi) and whether pressure overload-induced LV hypertrophy (LVH) might...

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Detaylı Bibliyografya
Asıl Yazarlar: Kindo, Michel, Gerelli, Sébastien, Bouitbir, Jamal, Charles, Anne-Laure, Zoll, Joffrey, Hoang Minh, Tam, Monassier, Laurent, Favret, Fabrice, Piquard, François, Geny, Bernard
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2012
Konular:
Physiology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428974/
https://ncbi.nlm.nih.gov/pubmed/22934079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2012.00332
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