Pressure overload-induced mild cardiac hypertrophy reduces left ventricular transmural differences in mitochondrial respiratory chain activity and increases oxidative stress

Objective: Increased mechanical stress and contractility characterizes normal left ventricular (LV) subendocardium (Endo) but whether Endo mitochondrial respiratory chain complex activities is reduced as compared to subepicardium (Epi) and whether pressure overload-induced LV hypertrophy (LVH) might...

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Detalhes bibliográficos
Main Authors: Kindo, Michel, Gerelli, Sébastien, Bouitbir, Jamal, Charles, Anne-Laure, Zoll, Joffrey, Hoang Minh, Tam, Monassier, Laurent, Favret, Fabrice, Piquard, François, Geny, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2012
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428974/
https://ncbi.nlm.nih.gov/pubmed/22934079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2012.00332
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