Pressure overload-induced mild cardiac hypertrophy reduces left ventricular transmural differences in mitochondrial respiratory chain activity and increases oxidative stress

Objective: Increased mechanical stress and contractility characterizes normal left ventricular (LV) subendocardium (Endo) but whether Endo mitochondrial respiratory chain complex activities is reduced as compared to subepicardium (Epi) and whether pressure overload-induced LV hypertrophy (LVH) might...

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Bibliographische Detailangaben
Hauptverfasser: Kindo, Michel, Gerelli, Sébastien, Bouitbir, Jamal, Charles, Anne-Laure, Zoll, Joffrey, Hoang Minh, Tam, Monassier, Laurent, Favret, Fabrice, Piquard, François, Geny, Bernard
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2012
Schlagworte:
Physiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428974/
https://ncbi.nlm.nih.gov/pubmed/22934079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2012.00332
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