Sodium nitroprusside induces cell death and cytoskeleton degradation in adult rat cardiomyocytes in vitro: implications for anthracycline-induced cardiotoxicity

Sodium nitroprusside (SNP) is used clinically as a rapid-acting vasodilator and in experimental models as donor of nitric oxide (NO). High concentrations of NO have been reported to induce cardiotoxic effects including apoptosis by the formation of reactive oxygen species. We have therefore investig...

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Bibliografski detalji
Glavni autori: Chiusa, M., Timolati, F., Perriard, J.C., Suter, T.M., Zuppinger, C.
Format: Artigo
Jezik:Inglês
Izdano: PAGEPress Publications 2012
Teme:
Original Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428964/
https://ncbi.nlm.nih.gov/pubmed/22688296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4081/ejh.2012.e15
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