Sodium nitroprusside induces cell death and cytoskeleton degradation in adult rat cardiomyocytes in vitro: implications for anthracycline-induced cardiotoxicity

Sodium nitroprusside (SNP) is used clinically as a rapid-acting vasodilator and in experimental models as donor of nitric oxide (NO). High concentrations of NO have been reported to induce cardiotoxic effects including apoptosis by the formation of reactive oxygen species. We have therefore investig...

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Detalhes bibliográficos
Main Authors: Chiusa, M., Timolati, F., Perriard, J.C., Suter, T.M., Zuppinger, C.
Formato: Artigo
Idioma:Inglês
Publicado em: PAGEPress Publications 2012
Assuntos:
Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428964/
https://ncbi.nlm.nih.gov/pubmed/22688296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4081/ejh.2012.e15
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