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The role of cell death and myofibrillar damage in contractile dysfunction of long-term cultured adult cardiomyocytes exposed to doxorubicin

In failing hearts cardiomyocytes undergo alterations in cytoskeleton structure, contractility and viability. It is not known presently, how stress-induced changes of myofibrils correlate with markers for cell death and contractile function in cardiomyocytes. Therefore, we have studied the progressio...

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Autori principali: Timolati, Francesco, Anliker, Tobias, Groppalli, Vittoria, Perriard, Jean-Claude, Eppenberger, Hans M., Suter, Thomas M., Zuppinger, Christian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Netherlands 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795142/
https://ncbi.nlm.nih.gov/pubmed/19890731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-009-9238-4
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