MyD88 inhibition amplifies dendritic cell capacity to promote pancreatic carcinogenesis via Th2 cells

The transition of chronic pancreatic fibroinflammatory disease to neoplasia is a primary example of the paradigm linking inflammation to carcinogenesis. However, the cellular and molecular mediators bridging these entities are not well understood. Because TLR4 ligation can exacerbate pancreatic infl...

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Detalhes bibliográficos
Main Authors: Ochi, Atsuo, Nguyen, Andrew H., Bedrosian, Andrea S., Mushlin, Harry M., Zarbakhsh, Saman, Barilla, Rocky, Zambirinis, Constantinos P., Fallon, Nina C., Rehman, Adeel, Pylayeva-Gupta, Yuliya, Badar, Sana, Hajdu, Cristina H., Frey, Alan B., Bar-Sagi, Dafna, Miller, George
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428946/
https://ncbi.nlm.nih.gov/pubmed/22908323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20111706
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