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Zinc finger transcription factor zDC is a negative regulator required to prevent activation of classical dendritic cells in the steady state
Classical dendritic cells (cDCs) process and present antigens to T cells. Under steady-state conditions, antigen presentation by cDCs induces tolerance. In contrast, during infection or inflammation, cDCs become activated, express higher levels of cell surface MHC molecules, and induce strong adapti...
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3428942/ https://ncbi.nlm.nih.gov/pubmed/22851594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20121003 |
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