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Route of antigen uptake differentially impacts presentation by dendritic cells and activated monocytes

Dendritic cells (DCs), which maintain tolerance and orchestrate T cell immune responses, comprise a heterogeneous group of cells. For example, in the steady state, murine spleen contains pre-DC-derived CD8(+) and CD8(−) conventional DCs. During inflammation, monocytes become activated and acquire so...

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Detalhes bibliográficos
Main Authors: Kamphorst, Alice O., Guermonprez, Pierre, Dudziak, Diana, Nussenzweig, Michel C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013633/
https://ncbi.nlm.nih.gov/pubmed/20729332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001205
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