Zinc finger transcription factor zDC is a negative regulator required to prevent activation of classical dendritic cells in the steady state

Classical dendritic cells (cDCs) process and present antigens to T cells. Under steady-state conditions, antigen presentation by cDCs induces tolerance. In contrast, during infection or inflammation, cDCs become activated, express higher levels of cell surface MHC molecules, and induce strong adapti...

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Bibliographic Details
Main Authors: Meredith, Matthew M., Liu, Kang, Kamphorst, Alice O., Idoyaga, Juliana, Yamane, Arito, Guermonprez, Pierre, Rihn, Suzannah, Yao, Kai-Hui, Silva, Israel T., Oliveira, Thiago Y., Skokos, Dimitris, Casellas, Rafael, Nussenzweig, Michel C.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428942/
https://ncbi.nlm.nih.gov/pubmed/22851594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20121003
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