Laddar...

Smad3 binding to the foxp3 enhancer is dispensable for the development of regulatory T cells with the exception of the gut

Regulatory T cells (T reg cells) are essential for the prevention of autoimmunity throughout life. T reg cell development occurs intrathymically but a subset of T reg cells can also differentiate from naive T cells in the periphery. In vitro, Smad signaling facilitates conversion of naive T cells in...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Schlenner, Susan M., Weigmann, Benno, Ruan, Qingguo, Chen, Youhai, von Boehmer, Harald
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428940/
https://ncbi.nlm.nih.gov/pubmed/22908322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20112646
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!