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Structure of the Sensor Domain of Mycobacterium tuberculosis PknH Receptor Kinase Reveals a Conserved Binding Cleft

Since their discovery over twenty years ago, eukaryotic-like transmembrane receptor Ser/Thr protein kinases (STPKs) have been shown to play critical roles in the virulence, growth, persistence and reactivation of many bacteria. Information regarding the signals transmitted by these proteins, however...

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Autors principals: Cavazos, Alexandra, Prigozhin, Daniil M., Alber, Tom
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428515/
https://ncbi.nlm.nih.gov/pubmed/22727744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.06.011
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