Independent genomic polymorphisms in the PknH serine threonine kinase locus during evolution of the Mycobacterium tuberculosis Complex affect virulence and host preference

Species belonging to the Mycobacterium tuberculosis Complex (MTBC) show more than 99% genetic identity but exhibit distinct host preference and virulence. The molecular genetic changes that underly host specificity and infection phenotype within MTBC members have not been fully elucidated. Here, we...

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Udgivet i:PLoS Pathog
Main Authors: Mata, Elena, Farrell, Damien, Ma, Ruoyao, Uranga, Santiago, Gomez, Ana Belen, Monzon, Marta, Badiola, Juan, Anel, Alberto, Gonzalo-Asensio, Jesús, Martin, Carlos, Gordon, Stephen V., Aguilo, Nacho
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7785237/
https://ncbi.nlm.nih.gov/pubmed/33347499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009061
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