Independent genomic polymorphisms in the PknH serine threonine kinase locus during evolution of the Mycobacterium tuberculosis Complex affect virulence and host preference

Species belonging to the Mycobacterium tuberculosis Complex (MTBC) show more than 99% genetic identity but exhibit distinct host preference and virulence. The molecular genetic changes that underly host specificity and infection phenotype within MTBC members have not been fully elucidated. Here, we...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS Pathog
Päätekijät: Mata, Elena, Farrell, Damien, Ma, Ruoyao, Uranga, Santiago, Gomez, Ana Belen, Monzon, Marta, Badiola, Juan, Anel, Alberto, Gonzalo-Asensio, Jesús, Martin, Carlos, Gordon, Stephen V., Aguilo, Nacho
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2020
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7785237/
https://ncbi.nlm.nih.gov/pubmed/33347499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009061
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