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Autonomic neurocristopathy-associated mutations in PHOX2B dysregulate Sox10 expression

The most common forms of neurocristopathy in the autonomic nervous system are Hirschsprung disease (HSCR), resulting in congenital loss of enteric ganglia, and neuroblastoma (NB), childhood tumors originating from the sympathetic ganglia and adrenal medulla. The risk for these diseases dramatically...

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Bibliografski detalji
Glavni autori: Nagashimada, Mayumi, Ohta, Hiroshi, Li, Chong, Nakao, Kazuki, Uesaka, Toshihiro, Brunet, Jean-François, Amiel, Jeanne, Trochet, Delphine, Wakayama, Teruhiko, Enomoto, Hideki
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428093/
https://ncbi.nlm.nih.gov/pubmed/22922260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI63401
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