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Neural Precursor Death Is Central to the Pathogenesis of Intestinal Aganglionosis in Ret Hypomorphic Mice
The RET tyrosine kinase is required for the migration, proliferation, and survival of the enteric neural crest-derived cells (ENCCs) that form the enteric nervous system (ENS). Hypomorphic RET alleles cause intestinal aganglionosis [Hirschsprung disease (HSCR)], in which delayed migration and succes...
में बचाया:
| में प्रकाशित: | J Neurosci |
|---|---|
| मुख्य लेखकों: | , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Society for Neuroscience
2010
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6632751/ https://ncbi.nlm.nih.gov/pubmed/20392943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6244-09.2010 |
| टैग : |
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